Lactic Acidosis In Critically Ill Patients
نویسندگان
چکیده
Lactic acidosis is defined as increase in blood lactate levels in association with acidemia. It should be suspected in all patients presenting with shock & decreased mayocardial contractility. The patients with lactic acidosis have high mortality. However, the prognosis and case fatality are completely dependent on underlying disease in each patient with lactic acidosis being an independent indicator of severity of shock. All efforts should be directed towards treatment of underlying cause and concomitant correction of acidosis.
منابع مشابه
Shoshin Beriberi in Critically-Ill patients: case series
Thiamine plays a fundamental role in cellular metabolism. The classical syndrome caused by thiamine deficiency is beriberi, and its fulminant variant, once considered an uncommon finding, is now encountered among the critically ill.We present a case series of four critically ill non-septic non-alcoholic patients with severe lactic acidosis and refractory cardio-circulatory collapse caused by ac...
متن کاملLactate versus non-lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients
INTRODUCTION Acid-base abnormalities are common in the intensive care unit (ICU). Differences in outcome exist between respiratory and metabolic acidosis in similar pH ranges. Some forms of metabolic acidosis (for example, lactate) seem to have worse outcomes than others (for example, chloride). The relative incidence of each type of disorder is unknown. We therefore designed this study to dete...
متن کاملRefractory Lactic Acidosis in Small Cell Carcinoma of the Lung
BACKGROUND Elevated lactate levels in critically ill patients are most often thought to be indicative of relative tissue hypoxia or type A lactic acidosis. Shock, severe anemia, and thromboembolic events can all cause elevated lactate due to tissue hypoperfusion, as well as the mitochondrial dysfunction thought to occur in sepsis and other critically ill states. Malignancy can also lead to elev...
متن کاملPrognosis of alcohol-associated lactic acidosis in critically ill patients: an 8-year study
Lactic acidosis is common in critical care; by contrast, a subtype called alcohol-associated lactic acidosis (AALA) is rarely encountered. The primary purpose of this study was to determine the prognosis of AALA in critically ill patients and the second aim was to determine whether the survival was associated to the peak blood lactate concentration. An 8-year retrospective analysis of adult pat...
متن کاملDysoxia and lactate.
Disturbances of oxygen supply or cellular oxygen metabolism are common in critically ill patients. An understanding of dysoxia, or oxygen limited energy depletion, requires an understanding of the normal physiology of cell oxygen metabolism, and the compensatory mechanisms that supply high energy molecules under conditions of hypoxia. Understanding disorders associated with hyperlactataemia req...
متن کامل